Indication name: Frontotemporal
dementia (FTD)
Frontotemporal dementia (FTD) – Market outlook, Epidemiology, Market
Forecast and Competitive Landscape Report – 2019 To 2030
Frontotemporal dementia (FTD) is a focal clinical syndrome
characterised by profound changes in personality and social conduct and
associated with circumscribed degeneration of the prefrontal and anterior
temporal cortex. Frontotemporal disorders can be grouped into three types-
Progressive behavior/personality
decline- changes in personality, behavior, emotions, and judgment (called
behavioral variant frontotemporal dementia).
Progressive language decline—
early changes in language ability, including speaking, understanding, reading,
and writing (called primary progressive aphasia).
Progressive motor
decline—characterized by various difficulties with physical movement, including
the use of one or more limbs, shaking, difficulty walking, frequent falls, and
poor coordination (called corticobasal syndrome, supranuclear palsy, or
amyotrophic lateral sclerosis).
Thelansis Epidemiology study
indicates In the USA the prevalence of FTD between the ages of 45–65 years
ranged from 15 to 22 per 100,000 people, with incidence estimates ranging from
2.7 to 4.1 per 100,000 members in the same age range.
Competitive landscape of FTD
includes country specific approved as well as pipeline therapies. Any asset/
product specific designation or review and Accelerated Approval are being
tracked and supplemented with analyst commentary.
KOLs
insights of FTD across 8 MM market from center of Excellence/ Public/
Private hospitals participated in the study. Insights around current treatment
landscape, epidemiology, clinical characteristics, future treatment paradigm
and Unmet needs.
FTD Market Forecast: Patient
Based Forecast Model (MS. Excel Based Automated Dashboard) which Data
Inputs with sourcing, Market Event and Product Event, Country specific Forecast
Model, Market uptake and patient share uptake , Attribute Analysis , Analog
Analysis , Disease burden and pricing scenario, Summary and Insights.
S. No Asset Company Stage
1 PR006 Prevail Therapeutics Phase 2
2 AL001 Alector Inc. Phase 3
3 TRx0237 TauRx Therapeutics Ltd Phase 3
4 galantamine hydrobromide Johnson & Johnson Phase 2
5 Flortaucipir F18 Avid Radiopharmaceuticals Phase 1
6 memantine hydrochloride H. Lundbeck A/S Phase 3
7 Hydroxypropyl-beta-cyclodextrin CTD Holdings, Inc. Phase 2
8 FRM-0334 FORUM Pharmaceuticals Inc Phase 2
9 IB1001 IntraBio Inc Phase 2
10 arimoclomol Orphazyme Phase 3
11 Adrabetadex Vtesse, Inc., Phase 3
12 AADvac1 40 µg Axon Neuroscience SE Phase 1
13 hematopoietic stem cell infusion Talaris Therapeutics Inc. Phase 2
14 GZ402665 Genzyme, a Sanofi Company Sanofi Phase 2
15 miglustat Actelion Phase 2
16 Pimavanserin ACADIA Pharmaceuticals Inc. Phase 3
17 Sebelipase alfa (SBC-102) Alexion Pharmaceuticals Phase 3
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