Indication name: Autosomal dominant
polycystic kidney disease (ADPKD)
Autosomal dominant polycystic
kidney disease (ADPKD) – Market outlook, Epidemiology, Market
Forecast and Competitive Landscape Report – 2019 To 2030
Autosomal dominant polycystic
kidney disease (ADPKD) is a genetic disorder characterized by
the formation of cysts within the kidneys, caused by genetic changes in the
PKD1, PKD2, GANAB and DNAJB11 genes. Thelansis Epidemiology study indicates
approximately one per 800-1000 population carries a mutation for this
condition. Approximately 85-90% of patients with ADPKD have ADPKD1; most of the
remaining patients have ADPKD2.
Competitive landscape of ADPKD
includes country specific approved as well as pipeline therapies. Any asset/
product specific designation or review and Accelerated Approval are being
tracked and supplemented with analyst commentary.
KOLs insights of ADPKD across 8
MM market from center of Excellence/ Public/ Private hospitals participated in
the study. Insights around current treatment landscape, epidemiology, clinical
characteristics, future treatment paradigm and Unmet needs.
ADPKD Market
Forecasting: Patient Based Forecast Model (MS. Excel Based Automated
Dashboard) which Data Inputs with sourcing , Market Event and Product Event ,
Country specific Forecast Model, Market uptake and patient share uptake ,
Attribute Analysis , Analog Analysis , Disease burden and pricing scenario,
Summary and Insights.
S. No Asset Company Partner Phase
1 Bardoxolone Methyl Reata Phase III
2 Venglustat malate Sanofi Phase III
3 Iixivaptan Palladio Phase II
4 Oxypurinol XORTX Pharma Phase II
5 Tesevatinib Kadmon/Symphony Evolution Phase II
6 RGLS-4326 Regulus Therapeutics Phase I
7 Ricolinostat Celgene/Regency Pharma Phase I
8 CFTR Signalsome Activators Discovery Biomed Pre-clinical
9 PKD-003 Goldfinch Bio Pre-clinical
10 PKD-004 Goldfinch Bio Pre-clinical
11 PKD-005 Goldfinch Bio Pre-clinical
12 Polycystic Kidney Disease Ttherapy Eloxx Pharma Pre-clinical
13 Apatone IC-MedTech Pre-clinical
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