Indication name: Stargardt
Disease
Stargardt Disease – Market
outlook, Epidemiology, Market Forecast and Competitive Landscape Report – 2020
To 2030 (Markets covered: US, Germany, France, Spain, United Kingdom, Italy,
Japan & China).
Stargardt disease is also called
Stargardt macular dystrophy, juvenile macular degeneration, or fundus
flavimaculatus. The disease causes progressive damage — or degeneration — of
the macula, which is a small area in the center of the retina that is
responsible for sharp, straight-ahead vision. In most cases, Stargardt macular
degeneration is caused by mutations in the ABCA4 gene. Less often, mutations in
the ELOVL4 gene cause this condition. The ABCA4 and ELOVL4 genes provide
instructions for making proteins that are found in light-sensing
(photoreceptor) cells in the retina.
According to Thelansis estimates,
Stargardt macular degeneration is the most common form of juvenile macular
degeneration, the signs and symptoms of which begin in childhood. The estimated
prevalence of Stargardt macular degeneration is 1 in 8,000 to 10,000
individuals.
Competitive landscape of
Stargardt Disease includes country specific approved as well as pipeline
therapies. Any asset/ product specific designation or review and Accelerated
Approval are being tracked and supplemented with analyst commentary.
Stargardt Disease Market
Forecast: Patient Based Forecast Model (MS. Excel Based Automated
Dashboard) which Data Inputs with sourcing, Market Event and Product Event,
Country specific Forecast Model, Market uptake and patient share uptake,
Attribute Analysis, Analog Analysis, Disease burden and pricing scenario,
Summary and Insights.
KOLs insights of Stargardt
Disease across 8 MM market from center of Excellence/ Public/ Private hospitals
participated in the study. Insights around current treatment landscape,
epidemiology, clinical characteristics, future treatment paradigm and Unmet
needs.
S. No Asset Company Partner Phase
1 ACU-4429 Kubota Pharmaceutical Holdings Co.,
Ltd. N/A III
2 Zimura Iveric Bio Archemix IIb
3 ALK-001 Alkeus Pharmaceuticals, Inc. N/A II
4 ASP7317 Astellas Pharma, Inc. CHA Bio & Diostech II
5 LBS-008 Lin Bioscience, Inc. N/A I
6 NSR-ABCA4 Biogen, Inc. N/A Preclinical
7 QRX-1011 ProQR Therapeutics N.V. N/A Preclinical
8 REV-0100 reVision Therapeutics, Inc. Cornell University Preclinical
9 Stargardt Program Applied Genetic Technologies
Corporation N/A Preclinical
10 STGD1 Minigene Program (IVERIC/UMass) Iveric Bio N/A Preclinical
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