Indication name: Spinal cord injury (SCI)
Spinal cord injury (SCI) – Market outlook, Epidemiology, Market Forecast
and Competitive Landscape Report – 2020 To 2030 (Markets covered: US, Germany,
France, Spain, United Kingdom, Italy, Japan & China).
A spinal
cord injury (SCI) is
damage to the spinal cord that results in a loss of function, such as mobility
and/or feeling. Spinal cord injuries are most often the result of vehicle
accidents, which account for 39.3% of SCI cases, followed closely by falls
(31.8%). Other causes include acts of violence (primarily gunshot wounds) at
13.5% and sports-related injuries at 8%.
Spinal cord injury can be classified into four categories: cervical,
thoracic, lumbar and sacral.
Cervical spinal cord injuries usually cause loss of function in the arms
and legs, resulting in quadriplegia
The 12 vertebra in the chest are called the thoracic vertebra.
The vertebra in the lower back between the thoracic vertebra, where the
ribs attach, and the pelvis (hip bone), are the lumbar vertebra.
The sacral vertebra run from the pelvis to the end of the spinal column.
SCIs are graded according to the American Spinal Injury Association
(ASIA) grading scale, which describes the severity of the injury. The scale is
graded with letters:
ASIA A: injury is complete spinal cord injury with no sensory or motor
function preserved.
ASIA B: a sensory incomplete injury with complete motor function loss.
ASIA C: a motor incomplete injury, where there is some movement, but
less than half the muscle groups are anti-gravity (can lift up against the
force of gravity with a full range of motion).
ASIA D: a motor incomplete injury with more than half of the muscle
groups are anti-gravity.
ASIA E: normal.
Epidemiology- According to Thelansis, an estimated 311,000 people in the United
States are living with spinal cord injuries (SCIs). There are approximately
19,350 new SCIs every year, most of which are caused by automobile accidents
and falls. About ~80% of new SCI cases are male.
Competitive landscape of Spinal cord injury (SCI) includes country
specific approved as well as pipeline therapies. Any asset/ product specific
designation or review and Accelerated Approval are being tracked and
supplemented with analyst commentary.
KOLs insights of Spinal cord injury (SCI) across 8 MM market from center
of Excellence/ Public/ Private hospitals participated in the study. KOL Insights around current treatment landscape,
epidemiology, clinical characteristics, future treatment paradigm and Unmet
needs.
Spinal cord injury (SCI) Market Forecast: Patient Based Forecast Model
(MS. Excel Based Automated Dashboard) which Data Inputs with sourcing, Market
Event and Product Event, Country specific Forecast Model, Market uptake and
patient share uptake, Attribute Analysis, Analog Analysis, Disease burden and
pricing scenario, Summary and Insights.
S. No Asset Company Stage
1 FAB117-HC Ferrer Internacional S.A. Phase 2
2 AXER-204 ReNetX Bio, Inc. Phase 2
3 KP-100IT Kringle Pharma, Inc. Phase 3
4 SC0806 and
rehabilitation BioArctic AB Phase 2
5 Cethrin Vertex Pharmaceuticals
Incorporated Phase 2
6 Neuro-Cells Neuroplast Phase 1
7 ES135 Eusol Biotech Co., Ltd. Phase 3
8 GRNOPC1 Lineage Cell Therapeutics, Inc. Phase 1
9 MT-3921 Mitsubishi Tanabe Pharma Development
America, Inc. Phase 2
10 Elezanumab AbbVie Phase 2
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