Indication name: Neuromyelitis
optica (NMO)
Neuromyelitis optica (NMO) – Market outlook, Epidemiology, Market Forecast and
Competitive Landscape Report – 2019 To 2030; (Markets covered: US, Germany,
France, Spain, United Kingdom, Italy, Japan & China)
Neuromyelitis optica (NMO) is an
autoimmune disease of the central nervous system (CNS) that predominantly
affects the optic nerves and spinal cord. It is sometimes also referred to as
NMO spectrum disorder. Neuromyelitis optica (NMO) is classified into relapsing
form- which has periodic flare-ups, with some recovery in between. This is the
more common kind, and women are far more likely to have this form than men.
Monophasic form- which involves a single attack that lasts a month or two. Men
and women get this type equally.
According to Thelansis there are
an estimated 4,000 people with NMO in the United States and a quarter-million
people worldwide. The prevalence of NMOSD is approximately 1.5 -11 per 100,000
individuals, although somewhat higher rates have been reported in countries
with a higher proportion of individuals of African ancestry.
Competitive landscape of Neuromyelitis
optica (NMO) includes country specific approved as well as pipeline therapies.
Any asset/ product specific designation or review and Accelerated Approval are
being tracked and supplemented with analyst commentary.
KOLs insights of
Neuromyelitis optica (NMO) across 8 MM market from center of Excellence/
Public/ Private hospitals participated in the study. Insights around current
treatment landscape, epidemiology, clinical characteristics, future treatment
paradigm and Unmet needs.
Biomarkers-AQP4-IgG, Th Lymphocytes,
Genetic biomarkers- HLA-DPB1,e52 HLA-DRB1*03:01,e53,e54 PD-1.3A allele of
PTPN22,e55 and CD226 Gly307Ser.e56 CYP7A1 gene G/G
Neuromyelitis optica (NMO) Market Forecasting: Patient
Based Forecast Model (MS. Excel Based Automated Dashboard) which Data Inputs
with sourcing , Market Event and Product Event , Country specific Forecast
Model, Market uptake and patient share uptake , Attribute Analysis , Analog
Analysis , Disease burden and pricing scenario, Summary and Insights.
S. No Asset Company Stage
1
Satralizumab Hoffmann-La
Roche Phase 3
2
Ravulizumab Alexion
Pharmaceuticals Phase 3
3
Inebilizumab MedImmune LLC
Phase 2
4
BAT4406F Bio-Thera
Solutions Phase 1
5
NPB-01 Nihon Pharmaceutical
Co., Ltd Phase 2
6
RC18 160 mg RemeGen Phase 3
7
HBM9161 Injection Harbour
BioMed (Guangzhou) Co. Ltd. Phase 1
8
SHR1459 Reistone Biopharma
Company Limited Phase 2
9
Dalfampridine Acorda
Therapeutics Phase 2
10 ABX-1431 HCl Abide Therapeutics Phase 1
11 BAF312 Novartis Pharmaceuticals Phase 2
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