Indication name: Lennox-Gastaut
syndrome (LGS)
Lennox-Gastaut
syndrome (LGS) – Market outlook, Epidemiology, Market Forecast and Competitive
Landscape Report – 2019 To 2030
Lennox-Gastaut syndrome (LGS) is a
severe form of epilepsy that typically becomes apparent during infancy or early
childhood. The most common causes are Structural brain abnormalities (most
common cause, 70% of cases), Genetic etiologies (de novo mutations) are
expected to account for many of the currently unexplained cases
Thelansis estimated incidence of
Lennox-Gastaut syndrome in 1 to 28 people per 100,000 and is believed to
account for 1-4 percent of all cases of childhood epilepsy. The annual
incidence in children is estimated to be 2 per 100,000 children. Onset of
Lennox-Gastaut syndrome is usually between 2-7 years with a peak onset between
3 to 5 years.
KOLs insights of LGS
across 8 MM market from center of Excellence/ Public/ Private hospitals
participated in the study. Insights around current treatment landscape,
epidemiology, clinical characteristics, future treatment paradigm and Unmet
needs.
Competitive landscape of LGS
includes country specific approved as well as pipeline therapies. Any asset/
product specific designation or review and Accelerated Approval are being
tracked and supplemented with analyst commentary.
LGS Market
Forecasting: Patient Based Forecast Model (MS. Excel Based Automated
Dashboard) which Data Inputs with sourcing , Market Event and Product Event ,
Country specific Forecast Model, Market uptake and patient share uptake ,
Attribute Analysis , Analog Analysis , Disease burden and pricing scenario,
Summary and Insights.
S. No Asset Company Partner Phase
1 Lamictal GlaxoSmithKline plc Aspen Pharmacare, Allergan Approved (Generic Competition)
2 Onfi H. Lundbeck A/S Daiichi Sankyo, Alfresa Pharma Approved (Generic Competition)
3 Topamax Johnson & Johnson Kyowa Hakko Kirin Approved (Generic
Competition)
4 Banzel Eisai Co., Ltd. Novartis, Acorda, Biotoscana Approved
5 Epidiolex GW Pharmaceuticals plc N/A
Approved
6 Qudexy XR Sawai Pharmaceutical Co., Ltd. N/A Approved
7 Sympazan Aquestive Therapeutics, Inc. N/A Approved
8 Trokendi XR Supernus Pharmaceuticals, Inc. Aequus Pharmaceuticals Approved
9 Fintepla Zogenix, Inc. Nippon Shinyaku III
10 Fycompa Eisai Co., Ltd. Hikma, Biotoscana III
11 OV935 Ovid Therapeutics, Inc. Takeda II
12 NRP2945 CuroNZ N/A Development Outside U.S.
13
Captisol-enabled Lamotrigine
CURx Pharmaceuticals, Inc.
Ligand Preclinical
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