Indication name: Lambert-Eaton Myasthenic Syndrome (LEMS)
Lambert-Eaton Myasthenic Syndrome
(LEMS) – Market outlook, Epidemiology, Market Forecast and Competitive
Landscape Report – 2020 To 2030 (Markets covered: US, Germany, France, Spain,
United Kingdom, Italy, Japan & China)
Lambert-Eaton myasthenic syndrome (LEMS)
is an autoimmune, presynaptic disorder of neuromuscular transmission
characterized by fluctuating muscle weakness and autonomic dysfunction
frequently associated with small-cell lung cancer (SCLC). Around 90% of LEMS
patients have pathogenic antibodies against the presynaptic P/Q-type
voltage-gate calcium channel (VGCC). Dysfunction or decrease in number of these
channels inhibits release of acetylcholine from the presynaptic endplate,
resulting in impaired neuromuscular transmission and muscle weakness.
According to Thelansis the
prevalence of Lambert-Eaton Myasthenic Syndrome (LEMS) is estimated to be between 1/250,000-
1/333,300 worldwide. There are approximately 400 known cases of LEMS in the
United States.
Competitive landscape of
Lambert-Eaton Myasthenic Syndrome (LEMS) includes country specific approved as
well as pipeline therapies. Any asset/ product specific designation or review
and Accelerated Approval are being tracked and supplemented with analyst commentary.
KOLs
insights of Lambert-Eaton Myasthenic Syndrome (LEMS) across 8 MM market
from center of Excellence/ Public/ Private hospitals participated in the study.
Insights around current treatment landscape, epidemiology, clinical
characteristics, future treatment paradigm and Unmet needs.
Lambert-Eaton Myasthenic Syndrome
(LEMS) Market Forecast: Patient Based Forecast Model (MS. Excel Based Automated
Dashboard) which Data Inputs with sourcing, Market Event and Product Event,
Country specific Forecast Model, Market uptake and patient share uptake,
Attribute Analysis, Analog Analysis, Disease burden and pricing scenario,
Summary and Insights.
S. No Asset Company Partner Phase
1 Firdapse Catalyst Pharmaceuticals, Inc. Jazz Pharmaceuticals Approved
2 Ruzurgi Jacobus Pharmaceutical Co. Inc N/A Approved"
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