Indication name: Autoimmune
Hepatitis (AIH)
Autoimmune Hepatitis (AIH) –
Market outlook, Epidemiology, Market Forecast and Competitive Landscape Report
– 2020 To 2030 (Markets covered: US, Germany, France, Spain, United Kingdom,
Italy, Japan & China).
Autoimmune hepatitis (AIH) is a
non-contagious, chronic, inflammatory, autoimmune disease in which one’s own
immune system attacks healthy, normal liver cells. AIH can be classified into
two clinically relevant types, Type 1 and 2, where AIH-1 represents about 80%
of AIH, and has a strong female predominance ~ 72% of affected people are
female. Type 1- also referred to as the classic type, is typically diagnosed in
adulthood. Type 2 autoimmune hepatitis is less common and generally affects
girls between the ages of 2 and 14, although it is probably underdiagnosed and
underreported.
Thelansis estimated in the US an
annual incidence of 1 per 200,000 cases whereas europe estimated 0.8 to 1.9
cases per 10,000 populations.
Autoimmune Hepatitis (AIH) genes
are located on the short arm of chromosome 6, within the human leukocyte
antigen (HLA) class II region, with particular regard to the ones encoding
allelic variants of DRB1.39 AIH-1 susceptibility has been associated with
DRB1*0301 and DRB1*040140,41 in white North American and Northern European
individuals and to DRB1*0405 and DRB1*0404 in Japan according to literature
survey.
Competitive landscape of
Autoimmune Hepatitis (AIH) includes country specific approved as well as
pipeline therapies. Any asset/ product specific designation or review and
Accelerated Approval are being tracked and supplemented with analyst
commentary.
Autoimmune Hepatitis (AIH) Market
Forecasting: Patient Based Forecast Model (MS. Excel Based Automated
Dashboard) which Data Inputs with sourcing, Market Event and Product Event,
Country specific Forecast Model, Market uptake and patient share uptake,
Attribute Analysis, Analog Analysis, Disease burden and pricing scenario,
Summary and Insights.
KOLs insights of Autoimmune
Hepatitis (AIH) across 8 MM market from center of Excellence/ Public/ Private
hospitals participated in the study. Insights around current treatment
landscape, epidemiology, clinical characteristics, future treatment paradigm
and Unmet needs.
S. No Asset Company
Stage
1 budesonide Dr. Falk Pharma GmbH Phase 3
2 VAY736 Novartis
Pharmaceuticals Phase 3
3 JKB-122 TaiwanJ Pharmaceuticals
Co. Phase 2
4 RO7049665 Hoffmann-La Roche Phase 2
5 sPIF BioIncept
LLC
Phase 1
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